Thứ Ba, 14 tháng 8, 2012

Hopefully eliminate HIV from the drug

(SKDS) - A research team from the University of North Carolina - United States conducted for 8 treatment of HIV with drug vorinostat. These patients were infected with blood cancer. Simultaneously with treatment with vorinostat to treat blood cancer, patients are counting on treatment with ARVs. Without the drug vorinostat, HIV-positive people will be forced to use ARVs for life.
Dr. David Margolis - a member of the team, said the results show that this is the first step to finding a cure HIV exclusion. So far, the HIV hiding inside some cells in the  


                                                                                          Mr. Timothy Brown - "The Berlin patient". 
human body without being detected, and suddenly activated again after a dormant period, is a major obstacle for the complete cure all HIV infected people.

In research published in the journal Nature, U.S. scientists said, was used to beat HIV drug vorinostat, in the resting state, cells from CD4 + T leukemia patient's body. That in principle, HIV will die very quickly in a few minutes after being pushed out of the cell where they are hiding. According to BS. David Margolis, with a single dose of vorinostat, HIV can be identified in a moment. Thus, this study shows that HIV can be identified with a drug.
Researcher John Frater - University of Oxford - confirmed the findings in the laboratory of Dr. David Margolis rekindle the spirit of those who are seeking a cure for HIV and called for stepped up research research in this direction. Quentin Sattentau immunologist said it was the study results promising, but also stressed that the above drugs may not be impacts to other types of cells containing HIV, such as cells in the brain such.
GS. Steve Deeks, along with Professor Françoise Barré - Sinoussi (Institut Pasteur - France), Nobel Prize in 2008 for his discovery of HIV (with French scientist Luc Montagnier), is hosting a global research strategy on the direction of Data eradicate HIV / AIDS. The team of scientists from the GS. Françoise Barré - Sinoussi has presented a new research strategy allows the international scientific groups to coordinate efforts to reach a decision in a discovery from the field has long been considered "impossible": destroyed by HIV.
Besides the two studies by the Institute Pasteur (France) on the autoimmune patients with HIV (the group of 12 patients developed a natural defense mechanism against HIV) and the University of California on anti-leukemia drugs to HIV knocked out of the host cell, a third case the attention that two HIV-infected patients have developed a new anti-HIV immune system after spinal cord transplantation. However, according to the researchers, the marrow transplant is a medical intervention is costly, complex and dangerous, can not be widely applied for 35 million HIV sufferers worldwide. Therefore, strategies for prevention and treatment is essentially finding a preventive vaccine for HIV negative people and a treatment for those infected with HIV.
So far, the only cure for HIV is considered to be purely American citizen Timothy Brown, also nicknamed the "Berlin patient". Diagnosed HIV positive in 1995, while still a student in Berlin, Timothy Brown shows no signs of infection since 2007, after bone marrow transplant to treat leukemia. The spinal cord that "Berlin patient" received from a person's body to, have an immune system resistant to HIV. According to estimates, about 0.3% of the world's population has natural immunity against HIV, this number may be 1% for residents of Europe, according to Mr. T. Brown.

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